Extraction of Hydroxyapatite from Bovine and Human Cortical Bone by Thermal Decomposition and Effect of Gamma Radiation: A Comparative Study

For the treatment of bone defect autogenous bone is most desirable, but there are several drawbacks and risks involved in using autogenic bone such as limited harvest due to insufficient donors, post-operative pain, increased blood loss, secondary surgical wounds and risk of thrombosis [3-5]. Allograft bone could overcome the above limitations, but it endures the risk of transmission of infection (e.g. HIV, Hepatitis etc.) [6-8]. another possible alternative of treatment for bone defect is xenogenous bone, which is morphologically and structurally similar to human bone. It is usually derived from bovine origin and easy to obtain, lower cost and available in unlimited supply.